Assumption #2: Some people may be predisposed depressive symptoms organically. For others, continued patterns of response to stress, trauma, and life events can contribute to a chemical imbalance or change in brain function.
This is a difficult assumption to address, because in a way we are attempting to explain what came first, the chicken or the egg. The answer to that question is… (drum roll) YES… both are true! It’s possible that some people are more at risk for experiencing depressive symptoms. Much attention has been given to genes and the role they play in predisposing individuals to depression. Research shows that genes can account for about 40% of the reason why some people suffer from symptoms of depression. I won’t pretend to know and write about all the medical reasons why this is so, I will simply mention one area that has received particular attention -The serotonin transporter gene.
As the name explains, this gene affects the function of serotonin in the brain. Serotonin is the chemical messenger that plays an important role in shutting down the stress response circuits and reducing anxiety. Some people who suffer from depression appears to have a specific kind of this gene (short transporter gene), which affects the delivery of this chemical to the synapses. In effect, people who have this gene, appear to receive deficient doses of this “I feel good” chemical. This is why anti-depressants have become so popular, in that they attempt to address and fix this anomaly, by keeping the serotonin that’s produced in the synapse, there for a longer time. This is what people refer to as a chemical imbalance, the good news for people who seem to have this gene is this. There is medication and cognitive, behavioral, nutrition, exercise, and spiritual actions that you can take to affect the way you feel. Let’s turn to this part now.
I suggested at the top that, “continued patterns of response to stress, trauma, and life events can contribute to a chemical imbalance or change in brain function.” This, unfortunately, appears to be true. Researchers have found and clearly shown that individuals who experience and respond to stress and depressive symptoms in negative ways (avoidance, drinking, drugs, secrecy, shame, guilt, isolation, withdrawal), actually affect how their brain function. Much like an imprint, or rut. I suppose that sounds like bad news! but here is the good news. The same research has also yielded the opposite results. Positive response to symptoms (exercise, activity, social connections, sharing, therapy, cognitive restructuring, positive behaviors, good nutrition), also creates long lasting changes in the brain, or a positive imprint on the brain. The reality here is this… our brains are co
nstantly changing while we are busy behaving on a day to day basis. Remember that our brain is in the business of creating patterns, good or bad. The brain is not the judge of whether a pattern is good or not… you are. If patterns continue to lead to negative long term consequences, it means they are maladaptive, which means that we should get busy trying to change them to more positive habits. Let me share a quick analogy to summarize what I’m talking about: Your brain is like a jungle (that’s fun in and of itself). You, armed with a sharp machete, go to work clearing up forest to make a path. So you chop and walk through the vegetation, over and over and over and over, until a clear path through the forest can be seen. This is symbolic of a pattern. If this is a negative pattern, then it’s time for you to put a “no entrance” sign at the entrance of it, and start chopping away at a better path. Depressive symptoms are often caused and fueled by negative responses, time to go to work recognizing them, and changing them to better ones.
Action Now: Which patterns of behavior, paths through the forest, have you created that are maladaptive for you? Well, what are you waiting for, put a “no trespassing” sign in front and determine which path you will take instead.
Happy Day,